-On April 29th 2014 Marion Larat victim of pill Meliane spoke at General Meeting of Bayer, Cologne
-Article in Daily Mail about victims in Britain February 1st 2014:
-Marion Larat French young woman victim of 3rd generation pill Meliane, her book and her struggle for justice Oct. 2013
April 29, 2014, Marion Larat, who became disabled by birthcontrol pill Meliane spoke at the General Meeting of Bayer in Cologne, Germany.
She spoke in French and her speech was translated by a German victim of a birthcontrol pill.
SIN-NL will publish a translation in English as soon as possible.
Article in Daily Mail February 1st 2014:
Britains medication watchdog urges 60.000 gp’s to warn women of risks of 3rd generation anticonception pills: Evra Patch, Femodene, Gedarel, Katya, Marvelon, Mercilon, Millinette, Sunya, Triadene, Yasmin and Yaz.
Deadly risk of pill used by 1m women: Every GP in Britain told to warn about threat from popular contraceptive
•Bestselling brands of birth control tablets linked to fatal blood clots
•They are believed to double the risk compared to older varieties
•’Third-generation’ contraceptives caused 14 deaths a year in France
•UK doctors have been ordered to alert women to the alarming dangers
By Sanchez Manning and Stephen Adams
PUBLISHED: 22:05 GMT, 1 February 2014 | UPDATED: 17:05 GMT, 2 February 2014
A million women who take Britain’s most popular contraceptive pills are to be told they risk developing potentially fatal bloods clots.
All GPs have been ordered to warn patients that taking some of the bestselling brands of birth control tablets – including Yasmin, Femodene and Marvelon – means they are nearly twice as likely to suffer blood clots compared to those who use older varieties.
Scientists have found so-called third-generation contraceptives caused 14 deaths a year in France – and now doctors in the UK have been ordered to alert women to the alarming dangers.
Contraceptive risk: Some of the bestselling brands of birth control tablets – including Yasmin, Femodene and Marvelon – can increase the risk of blood clots GPs are warning
Doctors have also been told not to offer the newer types of pill to those at highest risk.
Britain’s drugs watchdog has written to the country’s 60,000 GPs telling them they must, for the first time, go through a checklist when prescribing the pills.
The aim is to ensure they are not given to women with a higher inherent risk of developing blood clots. And they have been told they should ‘carefully consider’ the risks when prescribing pills.
The move follows a report by the European Medicines Agency, which found that synthetic hormones used in third generation pills increased the chance of developing life-threatening deep vein thromboses (DVT) much more than previously thought.
These newer pills are prescribed about two million times a year. They are popular because they are less likely than their predecessors to cause side-effects such as weight gain, headaches, breast tenderness and hair growth.
But GPs have now been told they must fully inform women of the risks of taking different ‘combined hormonal contraceptives’, which contain synthetic versions of the female hormones oestrogen and progesterone.
‘I CAN’T BRING MY HELEN BACK’
The warning has come too late to save teacher Helen Thompson, who last month died from a clot, her devastated widower has said.
James, from Oxfordshire, added: ‘The doctors said all women on the pill are at a higher risk of clots, but they said it was incredibly rare.
‘What caused the clot 100 per cent we don’t know, and I don’t want to hurt myself by investigating further.’ A hospital scan revealed a clot on his 28-year-old wife’s brain, but she died within 24 hours of diagnosis.
DVTs, which typically form in the leg, can travel up blood vessels causing a potentially fatal blockage in the lung called a pulmonary embolism. They can also go up to the brain, triggering a stroke.
Risk factors include being older and overweight, smoking or being prone to a type of migraine.
Last night pharmaceutical giant Bayer, which makes Yasmin and Femodene, said it would be making blood clot warnings more prominent on its packets.
Dr Peter Swinyard, chairman of the Family Doctors’ Association, said the advice would change the way he would prescribe pills.
He said: ‘Whereas previously I would have used Yasmin or Femodene as first line because they’re more “lady friendly”, now I probably wouldn’t be as keen.’ However, he said that he would still offer both to patients.
The letter from watchdogs at the Medicines and Healthcare Products Regulatory Agency (MHRA), which went out on January 22, stated that the risk of developing a serious blood clot from taking any combined pill was still ‘small’ and that any woman who had been taking a particular pill without any problems ‘does not need to stop using it’.
The benefits ‘far outweigh the risk of serious side effects in most women,’ it went on. Being pregnant actually increases the risk of DVT far more than any pill.
But the letter warned doctors that ‘careful consideration’ should be given to each patient’s risk of developing DVT, as well as the different level of risk each type of pill held.
Doctors should ‘regularly reassess’ each woman’s risk and discuss with them of the potential dangers of the pills they were prescribing. Similar letters have gone out to doctors across Europe.
Taking third generation contraceptives increases the risk of clots six times compared to those taking no pills at all. The annual risk of a woman of childbearing age having a serious blood clot is 1 in 5,000 if she is not on a combined contraceptive pill, it said.
The risk triples to about 1 in 1,700 a year if she is taking one of the older forms of combined pill, and taking third generation pills means the risk doubles again, to as high as 1 in 800.
Previous advice from 2011 suggested that the risk of clots among those taking third-generation contraception was just 1 in 3,000.
Risk: Scientists have found so-called third-generation contraceptives, such as Yasmin caused 14 deaths a year in France
The European review was prompted by a report from France, which found that from 2000 to 2011, 2,529 cases of serious blood clots – just over 200 a year – were down to combined contraceptives.
Of those, 1,751 (146 a year) were due to third generation pills. These clots led to 20 deaths a year on average, 14 from newer versions of the pill and six from older versions.
The French authorities consequently told doctors to offer the newer pills only if their patients had first tried the old ones – a harder line than the MHRA has taken.
Doctors are still trying to understand the link between the newer pills and serious blood clots – but it is thought that it is the synthetic oestrogen which increases the risk.
The hormones which appear to cause raised risks, are: gestodene, desogestrel, drospirenone, etonogestrel and norelgestromin.
These are present in brands including: Evra Patch, Femodene, Gedarel, Katya, Marvelon, Mercilon, Millinette, Sunya, Triadene, Yasmin and Yaz.
Older and apparently safer forms of progesterone are: levonorgestrel, norgestimate and norethisterone.
Third generation pills were launched in the 1980s and official concerns were first raised about increased DVT risks in 1995.
Dr Sarah Branch of the MHRA said yesterday: ‘Women should continue to take their contraceptive pill.
These are very safe, highly effective medicines for preventing unintended pregnancy and the benefits associated with their use far outweigh the risk of blood clots.’
Dr Asma Khalid of Marie Stopes International, added: ‘Any method of contraception comes with its own benefits and possible side effects, and it’s important that women are given the information they need t make informed choices.’
Beauty queen had stroke at 17
Georgie Holland was left partially sighted after suffering a stroke at the age of 17.
She had been taking the contraceptive pill Yasmin for two years.
Now 19, she still has limited peripheral vision in both eyes, suffers from headaches and will have to take an aspirin every day for the rest of her life to thin her blood.
Her mother Kim said: ‘After what Georgie went through, I honestly don’t think Yasmin and these third-generation pills should still be available.
‘I would warn any parents of teenagers to consider the risks of contraception.’
Mrs Holland, 45, recalled how former beauty pageant winner Georgie, right, spent a week in hospital after she collapsed.
A scan revealed a blood clot in her brain, and doctors linked her stroke to the pill.
‘What happened to Georgie was devastating,’ said Mrs Holland from Kettering, Northamptonshire.
‘She dealt with it amazingly but it has changed her.’
France: October 2013 Book Marion Larat victim of 3rd generation birth control pill
Oct. 16th 2013 Marion Larat 26 years Bordeaux France published a book about her experiences as victim of a 3rd generation birth control pill.
In 2006 she became 65% disabled three weeks after taken a 3rd generation birth control pill prescribed by her physician. Her sister and parents support her in her struggle to end the use of 3rd and 4the generation birth control pills.
In this book Marion a young French woman (1987) tells us about an enormous medical tragedy which happened when she was 19 years old. She took Meliane an anticonceptionpill of the 3rd generation and had a stroke making her disabled for 65%. She suffers from partial aphasy, partial paralysis of her face, arm, and leg as well as epilepsy.
Her doctor who prescribed this pill did not warn her of the risks, nor checked if she had any physical risks to use this pill.
In 2010 when Marion requested another gynaecologist for prescription of the pill, he informed her that she has a genetic disorder which accentuates coagulation. Also he told her that this 3rd generation pill doubles the risk for venous thrombosis in comparison to 2nd generation anticonception pills, thus causing her stroke!
Marion was operated 9 times to alleviate the symptoms of her stroke and had months of rehabilitation training.
She was a brilliant student with a bright future ahead of her. She has started a commercial project in designing compression stockings.
Her stroke has made her determined to fight the injustice and she is the first French woman who is suing the manufacturer Bayer and the ANSM the French institute for medicationsafety who failed to issue adequate warnings. Many French women have followed her example and also sue Bayer.
Her book co-written by her elder sister Pauline is a well balanced personal report about all factual developments and her emotions. It also clearly states how much it has affected her parents and her sister. Marion is very clear about her situation: my life has changed for good and I will never pardon them. A must read for all women who think about anticonception and a must read for doctors and those who manufacture these pills and distribute them.
We strongly recommend to make an English translation of this book, to make it available to English readers.
Please read the interview in Nouvelle Observateur with this remarkable strong young woman.
Dans “La pilule est amère”, à paraître le 16 octobre 2013, la toute première victime des contraceptifs dernier cri à avoir porté plainte en France revient sur son combat.
- » Pourquoi il faut jeter sa pilule de dernière génération
- » Bruxelles impose à la France de remettre Diane 35 sur le marché
- » Pilules de 3e et 4e génération : la plongée s’accélère
Sans elle, les pilules de dernières générations, bien plus dangereuses que leurs aînées, seraient encore prescrites à la volée par des gynécos et généralistes anesthésiés par le marketing des labos. Il y a sept ans, Marion Larat, 26 ans aujourd’hui, était terrassée par un AVC dû à Meliane, un contraceptif de 3e génération. Son calvaire devenu combat, elle le relate dans “La pilule est amère” (1), un récit co-écrit avec sa sœur Pauline et préfacé par “son pote” Martin Hirsch, ex-Haut commissaire aux solidarités actives contre la pauvreté.
Lorsque “Le Nouvel Observateur” l’avait rencontrée l’hiver dernier chez elle à Bordeaux, cette grande brune au regard décidé était encore sous le choc du scandale sanitaire, de l’ampleur du Mediator, qu’elle venait de faire éclater. Pour la toute première fois en France, une jeune femme victime des contraceptifs dernier cri portait plainte contre le puissant laboratoire Bayer et le directeur de l’Agence du médicament pour “atteinte involontaire à l’intégrité de la personne humaine”. Marion, porteuse d’une anomalie génétique qui accentue la coagulation, n’aurait jamais dû prendre ce type de pilule, qui double le risque de thrombose veineuse par rapport à celles de 2e génération.
L’accident a fait de son corps, autrefois sportif, un champ de bataille. Il y a d’abord la bouche, dont les mots, entrecoupés d’un “enfin” mécanique, peinent à sortir pour cause d’aphasie. Le visage, le bras et la jambe qui se paralysent. Le crâne, percé d’un trou pour relâcher la pression dans le cerveau. Les crises d’épilepsie qui laissent KO. Le moral qui plonge. En tout, neuf opérations et des mois de rééducation. “Je ne suis pas vieille et pourtant, je ne peux plus ouvrir un pot de confiture”. Marion ne deviendra jamais cadre, comme ses brillantes études en classes préparatoires le laissaient présager. Mais celle que ces camarades de classe surnommaient “la chouchoute du prof” ne peut se résoudre à passer ses journées devant la télé.
“Je serai peut-être la prochaine présidente de la République”
Elle s’accroche à un projet : commercialiser des bas de contention customisés, qui changeraient des sinistres modèles d’hôpitaux. Cette idée lui vaut de devenir la première lauréate de l’Institut du service civique fondé par Martin Hirsch. Dans la foulée, elle rencontre François Hollande à qui elle lance, un brin frondeuse : “Qui sait ? Je serai peut-être la prochaine présidente de la République”.
En attendant, la lutte contre “le médicament toxique” continue. “Tu dis que la Marion d’avant est morte. Pourtant je t’entends faire l’intéressante sur les ondes”, écrit sa soeur. Marion l’aphasique est désormais le porte-voix de dizaines d’autres femmes, qui ont déposé plainte à leur tour. Son histoire, estime Martin Hirsch “devrait être enseignée au cours des études médicales et la lecture de son livre recommandée aux étudiants qui se destinent à la médecine.”
(1) Ed. Stock, sortie le 16 octobre 2013